Zoznam publikácií, kde boli použité produkty spoločnosti HUMAC s.r.o.:
Marcinčák, Slavomír; Semjon, Boris; Marcinčáková, Dana; Reitznerová, Anna; Mudroňová, Dagmar; Vašková, Janka; Nagy, Jozef
Humic Substances as a Feed Supplement and the Benefits of Produced Chicken Meat Journal Article
V: Life, vol. 13, iss. 4, 2023.
@article{nokey,
title = {Humic Substances as a Feed Supplement and the Benefits of Produced Chicken Meat},
author = {Slavomír Marcinčák and Boris Semjon and Dana Marcinčáková and Anna Reitznerová and Dagmar Mudroňová and Janka Vašková and Jozef Nagy},
doi = {10.3390/life13040927},
year = {2023},
date = {2023-04-01},
urldate = {2023-04-01},
journal = {Life},
volume = {13},
issue = {4},
abstract = {Humic substances with a high proportion of humic acids (more than 40%) have been classified by the European Commission as feed materials that can be used in animal nutrition since 2013. A protective effect on the intestinal mucosa, as well as anti-inflammatory, adsorptive and antimicrobial properties, were recorded. Nutrient absorption, nutritional status and the immune response in chickens supplemented with HSs were significantly improved. HSs have the ability to enhance protein digestion as well as the utilization of calcium and trace elements. They are known to improve feed digestibility as a result of maintaining an optimal pH in the gut, leading to lower levels of nitrogen excretion and less odor in the husbandry environment. HSs not only increase digestibility and result in greater utilization of the feed ration but also improve the overall quality of the meat produced. They increase the protein content and reduce the fat content in breast muscles. They also contribute to improving the sensory characteristics of the meat produced. Their antioxidant properties improve the oxidative stability of meat during storage. The influence of HSs on fatty acid composition may be one of the reasons that meat has a more beneficial effect on the health of consumers.},
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Hricikova, Simona; Kožárová, Ivona; Hudáková, Nikola; Reitznerová, Anna; Nagy, Jozef; Marcinčák, Slavomír
Humic Substances as a Versatile Intermediary Journal Article
V: Life, vol. 13, iss. 4, 2023.
@article{nokey,
title = {Humic Substances as a Versatile Intermediary},
author = {Simona Hricikova and Ivona Kožárová and Nikola Hudáková and Anna Reitznerová and Jozef Nagy and Slavomír Marcinčák },
doi = {10.3390/life13040858 },
year = {2023},
date = {2023-03-23},
journal = {Life},
volume = {13},
issue = {4},
abstract = {Humic substances are organic ubiquitous components arising in the process of chemical and microbiological oxidation, generally called humification, the second largest process of the carbon cycle. The beneficial properties of these various substances can be observed in many fields of life and health, whether it is the impact on the human organism, as prophylactic as well as the therapeutic effects; animal physiology and welfare, which is widely used in livestock farming; or the impact of humic substances on the environment and ecosystem in the context of renewal, fertilization and detoxification. Since animal health, human health and environmental health are interconnected and mutually influencing, this work brings insight into the excellence of the use of humic substances as a versatile mediator contributing to the promotion of One Health.},
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pubstate = {published},
tppubtype = {article}
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Bujňák, Lukáš; Šamudovská, Alena Hreško; Mudroňová, Dagmar; Naď, Pavel; Marcinčák, Slavomír; Maskaľová, Iveta; Harčárová, Michaela; Karaffová, Viera; Bartkovský, Martin
The Effect of Dietary Humic Substances on Cellular Immunity and Blood Characteristics in Piglets Journal Article
V: Agriculture, vol. 13, iss. 3, 2023.
@article{nokey,
title = {The Effect of Dietary Humic Substances on Cellular Immunity and Blood Characteristics in Piglets},
author = {Lukáš Bujňák and Alena Hreško Šamudovská and Dagmar Mudroňová and Pavel Naď and Slavomír Marcinčák and Iveta Maskaľová and Michaela Harčárová and Viera Karaffová and Martin Bartkovský },
doi = {10.3390/agriculture13030636},
year = {2023},
date = {2023-03-08},
journal = {Agriculture},
volume = {13},
issue = {3},
abstract = {This study’s objective was to determine the impact of dietary humic substances on immune response and blood profiles in piglets. A total of 24 crossbred piglets (Slovakian White × Landrace; 35 days old; average body weight of 11.67 kg) were allotted to two dietary groups with (experimental; 5 g·kg−1) or without (control; 0 g·kg−1) natural humic substances supplementation. In this study, we observed a significant increase of the proportion of CD4+CD8- lymphocytes (p < 0.001) in the experimental group. The results also showed a tendency for an increase of the phagocytic activity and the engulfing capacity of phagocytes and the numbers of the other monitored lymphocyte subpopulations (CD3+, CD21+, CD4-D8+, CD4+CD8+, CD4+CD25+) in piglets in the experimental group compared to the control group. Supplementation of humic substances increased serum alkaline phosphatase compared to the control group (p < 0.05). Other monitored blood parameters were not significantly affected by dietary treatment. It concluded that inclusion of humic substances in the diet of piglets could have a stimulating effect on cellular immunity, without a negative effect on haematological and biochemical parameters.},
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Mudroňová, Dagmar; Karaffová, Viera; Semjon, Boris; Naď, Pavel; Koščová, Jana; Bartkovský, Martin; Makiš, Andrej; Bujňák, Lukáš; Nagy, Jozef; Mojžišová, Jana; Marcinčák, Slavomír
Effects of Dietary Supplementation of Humic Substances on Production Parameters, Immune Status and Gut Microbiota of Laying Hens Journal Article
V: Agriculture, vol. 11, nie 8, pp. 744, 2021.
@article{Mudroov2021,
title = {Effects of Dietary Supplementation of Humic Substances on Production Parameters, Immune Status and Gut Microbiota of Laying Hens},
author = {Dagmar Mudroňová and Viera Karaffová and Boris Semjon and Pavel Naď and Jana Koščová and Martin Bartkovský and Andrej Makiš and Lukáš Bujňák and Jozef Nagy and Jana Mojžišová and Slavomír Marcinčák},
url = {https://doi.org/10.3390/agriculture11080744},
doi = {10.3390/agriculture11080744},
year = {2021},
date = {2021-08-01},
journal = {Agriculture},
volume = {11},
number = {8},
pages = {744},
publisher = {MDPI AG},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Hudák, Marek; Semjon, Boris; Marcinčáková, Dana; Bujňák, Lukáš; Naď, Pavel; Koréneková, Beáta; Nagy, Jozef; Bartkovský, Martin; Marcinčák, Slavomír
Effect of Broilers Chicken Diet Supplementation with Natural and Acidified Humic Substances on Quality of Produced Breast Meat Journal Article
V: Animals 2021, Vol. 11, Page 1087, vol. 11, iss. 4, pp. 1087, 2021, ISSN: 20762615.
@article{nokey,
title = {Effect of Broilers Chicken Diet Supplementation with Natural and Acidified Humic Substances on Quality of Produced Breast Meat},
author = {Marek Hudák and Boris Semjon and Dana Marcinčáková and Lukáš Bujňák and Pavel Naď and Beáta Koréneková and Jozef Nagy and Martin Bartkovský and Slavomír Marcinčák},
url = {https://www.mdpi.com/2076-2615/11/4/1087/htm https://www.mdpi.com/2076-2615/11/4/1087},
doi = {10.3390/ANI11041087},
issn = {20762615},
year = {2021},
date = {2021-01-01},
journal = {Animals 2021, Vol. 11, Page 1087},
volume = {11},
issue = {4},
pages = {1087},
publisher = {Multidisciplinary Digital Publishing Institute},
abstract = {This study was conducted to examine the effect of two humic substances (HS) supplemented in broilers’ diet on the breast meat quality of broiler chickens. In this experiment, 120 pieces of one-day-old COBB500 broiler chickens were used. Broilers were divided into three groups, each containing 40 birds with three replications (13, 13, and 14 per one pen). Fattening lasted 38 days. The first experimental diet was supplemented with 0.7% of HS (HS0.7) and the second was enriched with 0.7% of acidified HS (HSA0.7). The control group of broilers (C) was fed a basal diet without the addition of any supplements. HS0.7 samples had the highest total protein content and the lowest content of fat (p < 0.01). The effects of broiler diet and storage had a significant impact on the pH of breast samples, p < 0.001 and p < 0.05, respectively. Supplementation of HS in broiler diet positively affected the lipid oxidation of breast meat samples, as indicated by the lower malondialdehyde content (p < 0.05). HSA0.7 samples had significantly better juiciness after the storage period (p < 0.001). The quality of meat produced with supplementation of HS in broilers’ feed can be considered as valuable in human nutrition due to improved protein and fat content with decreased lipid oxidation.},
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pubstate = {published},
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Mudroňová, Dagmar; Karaffová, Viera; Pešulová, T.; Koščová, Jana; Maruščáková, I. Cingeľová; Bartkovský, Martin; Marcinčáková, Daniela; Ševčíková, Z.; Marcinčák, Slavomír
The effect of humic substances on gut microbiota and immune response of broilers Journal Article
V: Food and Agricultural Immunology, vol. 31, iss. 1, pp. 137-149, 2020, ISSN: 0954-0105.
@article{nokey,
title = {The effect of humic substances on gut microbiota and immune response of broilers},
author = {Dagmar Mudroňová and Viera Karaffová and T. Pešulová and Jana Koščová and I. Cingeľová Maruščáková and Martin Bartkovský and Daniela Marcinčáková and Z. Ševčíková and Slavomír Marcinčák},
url = {https://www.tandfonline.com/doi/full/10.1080/09540105.2019.1707780},
doi = {10.1080/09540105.2019.1707780},
issn = {0954-0105},
year = {2020},
date = {2020-01-01},
urldate = {2020-01-01},
journal = {Food and Agricultural Immunology},
volume = {31},
issue = {1},
pages = {137-149},
publisher = {Taylor and Francis Ltd.},
abstract = {The work focused on the study of the immunomodulatory and gut-protecting effect of humic substances (HS) in broilers. The diet of experimental chicks was enriched with 0.8% of HS. We noted that HS had a stimulatory effect on the phagocytic activity and the engulfing capacity of phagocytes, however, the level of oxidative burst of phagocytes was not affected. We observed a significant increase of CD4+: CD8+ lymphocyte ratio, an indicator of immune stimulation. HS did not influence the IgA gene expression. In contrast, we observed a significant increase in the expression of MUC-2 (intestinal mucin 2) gene, and a decrease in the expression of IGF-2 (insulin-like growth factor 2) and also AvBD2 (avian beta defensin 2) genes. A decreased Enterobacteriaceae counts in the gut of experimental animals showed a positive effect on intestinal microbiota. We confirmed a gut-protecting and an immunostimulatory effect of HS in broiler chickens.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Semjon, Boris; Marcinčáková, Dana; Koréneková, Beáta; Bartkovský, Martin; Nagy, Jozef; Turek, Peter; Marcinčák, Slavomír
V: Poultry Science, vol. 99, iss. 3, pp. 1750-1760, 2020, ISSN: 15253171.
@article{Semjon2020,
title = {Multiple factorial analysis of physicochemical and organoleptic properties of breast and thigh meat of broilers fed a diet supplemented with humic substances},
author = {Boris Semjon and Dana Marcinčáková and Beáta Koréneková and Martin Bartkovský and Jozef Nagy and Peter Turek and Slavomír Marcinčák},
doi = {10.1016/j.psj.2019.11.012},
issn = {15253171},
year = {2020},
date = {2020-01-01},
journal = {Poultry Science},
volume = {99},
issue = {3},
pages = {1750-1760},
publisher = {Elsevier Inc.},
abstract = {Multiple factor analysis was used for the examination of meat quality of broilers, the diet of which was supplemented with 0.8 and 1.0% addition of humic substances (HS). One hundred fifty COBB 500 one-day-old male broilers chicks were randomly divided into 3 different groups: one control and 2 experimental (n = 50), and they were fattened for 35 D. Subsequently, the meat quality was analyzed and defined by physicochemical and sensory quality, supplemented with analysis by instrumental methods. We observed changes in dry matter, fat, water, and protein content in experimental samples of breast and thigh meat (P < 0.001). In both experimental groups, the concentration of phosphates and pH decreased in breast meat (P < 0.001) and in thigh meat (P < 0.05). The smell of experimental chicken breast meat samples after cooking was evaluated by a sensory panel, which scored a higher point score than that of the control group (P < 0.05). Sensory evaluation of taste indicated a positive response with respect to the perception of meat quality in relation to a greater supplementation of HS in the diet. Thigh meat samples showed a variable extent of water loss after cooking, but lower values of water loss were generally obtained from thigh meat samples of poultry fed with higher HS supplementation, than in chicken breast meat samples. Significant differences in evaluated variables between both experimental groups were not observed. The color of breast meat samples changed, when considering the variables of lightness and redness, with the addition of 1% HS (P < 0.05). The main advantage of the breast meat of broilers fed a diet supplemented with HS was observed in the final meat quality, which was positively affected by increased protein and decreased fat content. Because of its nutritional composition, it can be considered to be rather a valuable type of meat in human nutrition than ordinarily.},
keywords = {},
pubstate = {published},
tppubtype = {article}
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Jaďuttová, Iveta; Marcinčáková, Dana; Bartkovský, Martin; Semjon, Boris; Harčárová, Michaela; Nagyová, Alena; Váczi, Peter; Marcinčák, Slavomír
V: Acta Veterinaria Brno, vol. 88, iss. 3, pp. 307-313, 2019, ISSN: 18017576.
@article{nokey,
title = {The effect of dietary humic substances on the fattening performance, carcass yield, blood biochemistry parameters and bone mineral profile of broiler chickens},
author = {Iveta Jaďuttová and Dana Marcinčáková and Martin Bartkovský and Boris Semjon and Michaela Harčárová and Alena Nagyová and Peter Váczi and Slavomír Marcinčák},
doi = {10.2754/avb201988030307},
issn = {18017576},
year = {2019},
date = {2019-01-01},
journal = {Acta Veterinaria Brno},
volume = {88},
issue = {3},
pages = {307-313},
publisher = {University of Veterinary and Pharmaceutical Sciences},
abstract = {Humic substances are currently being considered as a new feed component in replacement of antibiotic growth stimulators to improve growth and health in animals. The aim of our work was to evaluate the effect of the addition of humic substances to the feed at concentrations of 0.8% and 1.0% on the growth parameters, carcass yield, selected blood enzymes, minerals, and the bone quality in broiler chickens. One hundred fifty COBB 500 one-day-old male broiler chicks were randomly divided into one control and two experimental groups (n = 50) with three replications (16, 16 and 17 per pen), and fattened for 35 days. The broilers of the experimental groups (H0.8 and H1.0) were fed commercial feed mixtures with added humic substances (at 8 g·kg-1 and 10 g·kg-1). The control group was fed a diet without the addition of humic substances. A slight increase in the final body weight and feed conversion ratio was noted in the experimental groups (P > 0.05). Significantly higher yields of breast and thigh meat (P < 0.05) were recorded for the experimental group H1.0. The blood cholesterol level was lower for both experimental groups. A lower concentration of alkaline-phosphatase was observed in group H1.0. A decrease in aspartate aminotransferase and calcium was recorded for group H0.8. A significantly higher content of calcium and lower content of phosphorus was found in the bones of experimental animals. The 1% addition of humic substances had a positive impact on growth parameters (P > 0.05), improved selected blood indices and increased the calcium content in the bones of broilers (P < 0.05).},
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Vašková, Janka; Patlevič, Peter; Žatko, Daniel; Marcinčák, Slavomír; Vaško, Ladislav; Krempaská, Klára; Nagy, Jozef
Effect of humic acids on poultry under stress conditions Journal Article
V: SLOVENIAN VETERINARY RESEARCH, vol. 55, iss. 4, 2018, ISSN: 1580-4003.
@article{nokey,
title = {Effect of humic acids on poultry under stress conditions},
author = {Janka Vašková and Peter Patlevič and Daniel Žatko and Slavomír Marcinčák and Ladislav Vaško and Klára Krempaská and Jozef Nagy },
url = {https://slovetres.si/index.php/SVR/article/view/469},
doi = {10.26873/SVR-469-2018},
issn = {1580-4003},
year = {2018},
date = {2018-01-01},
urldate = {2018-01-01},
journal = {SLOVENIAN VETERINARY RESEARCH},
volume = {55},
issue = {4},
publisher = {University of Ljubljana, Veterinary Faculty},
abstract = {The transportation of chickens from the poultry farm to the slaughterhouse causes stress conditions that influence the oxidative status of the whole organism and subsequently change the organoleptic properties of the meat delivered to the consumer. The aim of this work was to investigate how administering 0.6% humic acids to broiler chickens for a period of 42 days affects the level of selected enzymes directly involved in oxidative stress elimination. For the most objective estimation of the oxidative state, parameters were determined in liver and kidney mitochondria, and in the blood plasma. With regards to the chelating properties of humic acids, our interest was in monitoring the effects on the distribution of the transition metals Fe, Zn, Cu, Mn, which serve as cofactors of antioxidant enzymes. We have found that, under normal conditions, 42 days of humic acid administration do not cause significant metal redistribution. It has a significant effect on Se excretion, according to the pronounced deposition of Se in kidney tissue, without significantly increased activity of the corresponding enzyme. This led to compensation by changes in other antioxidant enzyme activities. This is a noteworthy finding, especially after administration of longer than 42 days. In conditions caused by sudden stress, according to the detected element levels, it is possible to expect a better response in the case of humic acid administration. The effect of humic acid supplementation appeared to be organ-specific and may ultimately be beneficial for the chickens' health, stress elimination and, finally, the quality of the meat. Key words: antioxidant enzymes; humic acids; chicken; metal cofactors; oxidative stress UČINKI HUMINSKE KISLINE NA PERUTNINO V STRESNIH POGOJIH Povzetek: Prevoz piščancev s perutninske farme v klavnico povzroča stresne razmere, ki vplivajo na oksidativni status celotnega organizma in kasneje spremenijo organoleptične lastnosti mesa, dostavljenega potrošniku. Cilj raziskave je bil proučiti, ali dodajanje 0,6 % huminske kisline v hrano pitovnim piščancem za 42 dni vpliva na aktivnost nekaterih encimov, ki so neposredno vključeni v urejanje in zmanjševanje oksidativnega stresa. Za objektivno ocenjevanje oksidativnega stanja so se določevali parametri v jetrnih in ledvičnih mitohondrijih ter v krvni plazmi. Kelacijske lastnosti huminske kisline so bile proučevane s spremljanjem učinkov na porazdelitev prehodnih kovin Fe, Zn, Cu, Mn, ki služijo kot kofaktorji antioksidantnih encimov. Ugotovili so, da v normalnih pogojih 42-dnevno dodajanje huminske kisline ne povzroči bistvene prerazporeditve kovin. Dodajanje pa pomembno vpliva na izločanje Se glede na izrazito usedlino Se v tkivu ledvic, brez bistveno povečane aktivnosti ustreznega encima. To je privedlo do sprememb, ki so nadomestile aktivnosti drugih antioksidantnih encimov. To je pomembna ugotovitev, še posebej pri dodajanjih več kot 42 dni. V pogojih, ki jih povzroča nenadni stres, je glede na ugotovljene ravni elementov mogoče pričakovati boljši odziv pri uporabi huminske kisline. Učinek dopolnjevanja s huminsko kislino se je izkazal za organsko-specifičnega in je lahko koristen za zdravje piščancev, odpravo stresa in končno kakovost mesa. Ključne besede: antioksidativni encimi; humične kisline; piščanec; kovinski kofaktorji; oksidativni stres},
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tppubtype = {article}
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Vašková, Janka; Patlevič, Peter; Žatko, Daniel; Vaško, Ladislav; Marcinčák, Slavomír
Impact of humic acids on trace element content under different conditions Journal Article
V: Folia Veterinaria, vol. 59, iss. 3, pp. 159-164, 2015, ISSN: 0015-5748.
@article{nokey,
title = {Impact of humic acids on trace element content under different conditions},
author = {Janka Vašková and Peter Patlevič and Daniel Žatko and Ladislav Vaško and Slavomír Marcinčák},
issn = {0015-5748},
year = {2015},
date = {2015-01-01},
journal = {Folia Veterinaria},
volume = {59},
issue = {3},
pages = {159-164},
abstract = {The observations in mitochondria share a lot of similarities in trace element distribution with those observed previously in chicken bodies after humic acids supplementation. The redistribution in the levels of some elements, especially the overall increase in iron and decrease in selenium, could have important effects on the use of elements and the overall redox state of the organism. Based on our findings, it is necessary to consider the length of safe use, in addition to the level of dosage. After 42-days of supplementation with humic acid, according to the levels of trace elements found, an improved response of the organism to stress conditions can be expected.},
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pubstate = {published},
tppubtype = {article}
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Marcinčáková, Dana; Mačanga, Ján; Nagy, Jozef; Marcinčák, Slavomír; Popelka, Peter; Vašková, Janka; Jaďuttová, Iveta; Mellen, Martin
Effect of supplementation of the diet with humic acids on growth performance and carcass yield of broilers Journal Article
V: Folia Veterinaria, vol. 59, iss. 3, pp. 165-169, 2015, ISSN: 0015-5748.
@article{nokey,
title = {Effect of supplementation of the diet with humic acids on growth performance and carcass yield of broilers},
author = {Dana Marcinčáková and Ján Mačanga and Jozef Nagy and Slavomír Marcinčák and Peter Popelka and Janka Vašková and Iveta Jaďuttová and Martin Mellen},
issn = {0015-5748},
year = {2015},
date = {2015-01-01},
urldate = {2015-01-01},
journal = {Folia Veterinaria},
volume = {59},
issue = {3},
pages = {165-169},
abstract = {The aim of this study was to confirm the effects of
the product HUMAC Natur (humic acid source) supplemented to broiler feed during 39 days of fattening on the;
final body weight, carcass yield and percentage of the carcasses. Eighty broilers COBB 500 included in the experiment were fed commercial diet. Humic acids were added
to the feed of experimental broilers (n=40) as a 0.6%
concentrate, from the first day of fattening. On day 39
of fattening, the mean body weight of the experimental
broilers was lower (2498.0±244.6g) in comparison to the
control (2535.0±268.2g) (P>0.05). The addition of the
humic acid product to feed as a 0.6% concentrate affected
positively the carcass yield (P<0.05), but had no significant positive effect on the live body weight (P>0.05). The
mean weight of the breast and thigh muscles in the experimental and control groups was comparable.},
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pubstate = {published},
tppubtype = {article}
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the product HUMAC Natur (humic acid source) supplemented to broiler feed during 39 days of fattening on the;
final body weight, carcass yield and percentage of the carcasses. Eighty broilers COBB 500 included in the experiment were fed commercial diet. Humic acids were added
to the feed of experimental broilers (n=40) as a 0.6%
concentrate, from the first day of fattening. On day 39
of fattening, the mean body weight of the experimental
broilers was lower (2498.0±244.6g) in comparison to the
control (2535.0±268.2g) (P>0.05). The addition of the
humic acid product to feed as a 0.6% concentrate affected
positively the carcass yield (P<0.05), but had no significant positive effect on the live body weight (P>0.05). The
mean weight of the breast and thigh muscles in the experimental and control groups was comparable.
Top 10 autorov
1. Janka Vašková 122. Slavomír Marcinčák 11
3. Ladislav Vaško 9
4. Lukáš Bujňák 8
5. Pavel Naď 7
6. Jozef Nagy 7
7. Daniel Žatko 6
8. Martin Bartkovský 6
9. Štefan Tóth 6
10. Boris Semjon 5